ArteFill® is the first permanent FDA-approved injectable filler. ArteFill® contains PMMA (polymethylmethacrylate) microspheres and purified bovine collagen gel with an anesthetic. PMMA is one of the most widely used substances in medical implants with a proven safety record for over 60 years.
After an ArteFill® injection the microspheres that are suspended in the collagen become part of the patient's own tissue as the collagen is resorbed, filling in the wrinkle for enduring correction.
Unlike the other injectable fillers that are resorbed by the body during the months following each treatment, the microspheres in ArteFill® provide permanent support and results continue to improve over several months.
Depending on the depth of their wrinkles and the amount of Artefill used with each treatment, most people get the results they want with one or two treatments!